BioStream
BioStream is a low-pressure chromatography system developed with YMC's rich product experience and mature technology. It combines excellent operability, high quality, and high performance. BioStream is best suited for separation and purification in the downstream processes of biopharmaceutical manufacturing, such as ion exchange chromatography and size exclusion chromatography. Completely meets the requirements of hygiene, speed, and high purity in the separation and purification of antibodies and other biopharmaceuticals. We offer a wide range of specifications to choose from, from development to GMP manufacturing.
Product Information Product Model flow path composition
Product Features
Best suited for purification of downstream processes in biopharmaceutical manufacturing
Made in Japan based on cGMP standards, explosion-proof function can be supported
Excellent washing ability and good hygiene for CIP/SIP
Equipped with the industry's largest class 21.5-inch touch screen, the operation performance is outstanding.
Low pulsation of flow with multiple diaphragm pumps
Can support IQ/OQ test, CSV format
Product Use
Separation of peptides and proteins
Separation of food, pharmaceutical and pesticide decomposition products
Separation of fermentation products
Product Speciality
Touch screen interface, easy to operate
The system operation adopts a 21.5-inch touch screen, which provides a good visual and sensory experience of operation. On the main control screen, the corresponding actions and the current status of each sensor can be seen at a glance. The icons in the flow chart screen (upper part) allow you to switch the flow path and control the flow rate in the pump operation panel.
High degree of freedom in running the program
You can check the settings of "event", "collector condition", "delivery condition", and "alarm condition" on the same screen, and generate the desired program intuitively and easily. By checking the flow chart generated from the set program, you can ensure that the program settings are as expected. 1. Event Setting (upper left table) to complete the setting of flow path switching, termination conditions, marking lines, etc. 2. Liquid delivery setting (lower left table) completes the setting of the flow rate. 3. collector setting (upper right form) completes the setting of the collection port switching conditions. 4. Alarm setting (center right form) completes the setting of alarm conditions. 5. Flow chart to check the flow rate settings
Precise flow control
The use of a 5-connected oil-free diaphragm pump minimizes pulsation and provides peace of mind in production. The servo-motor type pump control is supplemented by a flow meter for feedback, realizing high-precision flow control.
Rich configuration options
High-pressure hook-up function: add 1 main pump. High-precision high-pressure flow hookup is realized by feedback operation. 1. Pressure gauge addition: set on the outlet side of the column. Display the residual pressure in the line. 2. Thermometer: set on the inlet side of the column. The temperature inside the line is displayed. 3. external interface add-on: set on the inlet side of the column to add a filter inside the flow line. 4. External port add-on: External port set on the inlet side of the column to add filters inside the flow path. 5. Collection port add-on: Maximum 10 collection ports can be supported.
Regulatory support
1. GMP: Propose various certificates and evaluate their suitability at each stage of implementation. 2. CSV: Building a life cycle model for development and inspection, and verifying it at each stage. 3. Electronic Signature: Login management by combining account and password for 4 types of operating privileges 4. Electronic records: authenticity, visibility, preservation, automatic backup, connection limitation, time watermarking, reviewability.